It is recommended for second-stage or in-depth assessments and/or for particular research evaluations rather than for applications in routine care settings. The ADAS-COG is used for comprehensive cognitive assessment. Cognitive Tests to Detect Dementia: A Systematic Review and Meta-analysis. Dementia and Geriatric Cognitive Disorders, 36(3–4), 242. Validation of the Addenbrooke’s Cognitive Examination III in frontotemporal dementia and Alzheimer’s disease. Hsieh, S., Schubert, S., Hoon, C., Mioshi, E., & Hodges, J.For other uses, please contact the original authors to seek permission. The ACE-III can be used for free in clinical practice and research projects. The ACE-III is administered by healthcare professionals. It is useful for differential diagnosis between Alzheimer’s disease (AD), frontotemporal dementia (FTD), Parkinson’s disease dementia and related neurodegenerative conditions. The ACE-III is a comprehensive screening tool that is the recommended instrument for all dementias when shorter screens are inconclusive.